I’ve stayed away from the anti-depressants and the big three; Lyrica, Cymbalta and Savella drugs prescribed to treat fibromyalgia symptoms.  I had determined early on that I would only take old school meds, medications that had been around for a long time.

But it looks like there may be a new drug coming out of Japan that’s tackling the neurologic side of things.

Crazy painA Japanese drug company, Daiichi Sankyo, is conducting clinical trials on mirogabalin, a new drug that could finally give fibromyalgia sufferers an alternative to the three approved medications — which often don’t work or have too many side effects.

Daiichi Sankyo is currently enrolling patients in the “ALDAY” study, a large Phase III clinical trial evaluating the safety and efficacy of mirogabalin in treating pain from fibromyalgia. About 4,000 patients will be studied at 800 clinical centers in 40 different countries.

A unique aspect of the ALDAY study is that it pits mirogabalin head to head against Lyrica (pregabalin), the top-selling fibromyalgiamedication.  Both drugs bind to calcium channels that are believed to cause neuropathic pain. An earlier Phase II study suggested that mirogabalin may be 17 times more effective than Lyrica, although some critics questioned whether the design of the study was fair.

Advanced trials are also underway in Asia evaluating mirogabalin in the treatment of pain from diabetic peripheral neuralgia and postherpetic neuralgia (shingles).

“Pain associated with the neurologic conditions of diabetic peripheral neuropathic pain, postherpetic neuralgia and fibromyalgia can be debilitating,” said Lesley Arnold, MD, Professor of Psychiatry and Behavioral Neuroscience and Director of the Women’s Health Research Program, University of Cincinnati and lead investigator of the ALDAY program. “New treatment options are needed to help people living with these neurologic conditions relieve and manage their chronic pain and hopefully, improve their function and quality of life.”

I truly hope they found something that works that doesn’t come with the long list of side-effects the Big three do.

Whats your experience with these drugs and are you wiling to try something new? Share your experience and insights in the comments below and help others to Live Well with Fibro.

To learn more about the ALDAY program, click here to visit Pain News Network.

This is republished article. Originally this article was published by http://www.fabandfitwithfibro.com